Texas A&M Biologists Uncover Protein Essential to Clock Gene Expression Repression in Monarch Butterflies

Jan 31, 2022
"My two primary collaborators happen to be the ones who contributed in large part to our knowledge regarding PER function in repression in fruit flies as members of Michael Rosbash's lab at Brandeis. Paul Hardin showed that PER was a circadian repressor and discovered the concept of the feedback loop which later led to the 2017 Nobel Prize, and Jerome Menet showed that PER was responsible for removing CLK:BMAL1 off-DNA. What none of us anticipated was that the Monarch butterfly would be the one unveiling new secrets behind PER mode of action in the clockwork."
Dr. Christine Merlin, Texas A&M biologist